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Frequently asked questions

Our Scientific Applications Support team has assembled a list of frequently asked questions to help you find answers quickly. Filter using one or more categories to focus on specific topics, or use the search bar to perform a text search.

What makes Alt-R® S.p. HiFi Cas9 Nuclease 3NLS a high fidelity enzyme?

Alt-R S.p. HiFi Cas9 Nuclease 3NLS contains proprietary mutations that reduce cutting at problematic off-target sites, while maintaining similar on-target potency.

*RUO—For research use only. Not for use in diagnostic procedures. Unless otherwise agreed to in writing, IDT does not intend for these products to be used in clinical applications and does not warrant their fitness or suitability for any clinical diagnostic use. Purchaser is solely responsible for all decisions regarding the use of these products and any associated regulatory or legal obligations.